Syllabus
General Information
Structure of GATE & GATE Results
Important Tips for GATE
GATE PAPERS
2013 (Solved with Explanations)
2012 (Solved with Explanations)
CONTENTS
GATE BIOTECHNOLOGY
SECTION I : BIOTECHNOLOGY
Chapter - 1 Biomolecules : Constituents of Life
1.1 Carbohydrates
1.2 Lipids
1.3 Amino acids
1.4 Proteins
1.5 Nucleic acid
1.6 Vitamins
Chapter - 2 Bioenergetics and Metabolism
2.1 Bioenergetics
2.2 Metabolism
2.3 Photosynthesis
2.4 Nitrogen fixation and assimilation
2.5 Objective questions, answers and explanations
Chapter - 3 Biophysical and Biochemical Techniques
3.1 Microscopy
3.2 Centrifugation
3.3 Dialysis and molecular filtration
3.4 Chromatography
3.5 Electrophoresis
3.6 Spectroscopy
3.7 Autoradiography
3.8 Biochemical Tests : amino acids, carbohydrate and lipids
3.9 Objective questions, answers and explanations
Chapter - 4 Cell Biology
4.1 Introduction
4.2 Organisation of eukaryotic cell
4.3 Cell growth and cell division
Chapter - 5 Microbiology
5.1 Prokaryotes : Phylogenetic overview
5.2 Structure of bacterial cell
5.3 Bacterial cell envelope and cell wall synthesis
5.4 Bacterial movement and chemotaxis
5.5 Bacterial nutrition and growth
5.6 Bacterial genome : Bacterial chromosome and plasmid
5.7 Recombination and gene transfer
5.7.1 Exchange of genetic information
5.8 Bacterial Taxonomy
5.9 General feature of important bacterial group
5.10 Archaeobacteria
5.11 Bacterial toxins
5.12 Control of microorganisms
5.13 Applications of microorganisms : Antibiotics
5.14 Viruses
5.14.1 Structural features of viruses
5.14.2 Classification of viruses
5.14.3 Families of viruses of human diseases
5.15 Viroids and Prions
5.16 Virus multiplication
5.17 AIDS and HIV
5.18 Objective questions, answers and explanations
Chapter - 6 Immunology
6.1 Immune system
6.2 Innate immunity
6.3 Adaptive immunity
6.4 Cells of the immune system
6.5 Organs of immune system and their functions
6.6 Antigens
6.6.1 General properties of antigen
6.7 B-cell and T-cell epitopes
6.8 Superantigens
6.9 Haptens
6.10 Adjuvants
6.11 Major histocompatability complex and antigen processing & presentation
6.12 Antibody structure, function and diversity
6.13 T cells : Receptors and activation
6.14 B cells : Maturation and activation
6.15 Polyclonal antibody
6.16 Monoclonal antibody
6.17 Antibody diversity/Antibody genes
6.18 Cytokines
6.19 Molecules of the innate immunity
6.20 Acute phase proteins
6.21 Hypersensitive reactions
6.22 Autoimmunity
6.23 Transplantation immunology
6.24 Vaccines
6.25 Immunodeficiency diseases
6.26 Immunological techniques
6.27 Objective questions, answers and explanations
Chapter - 7 Genetics - I : Classical and Population Genetics
7.1 Classical Genetics
7.2 Population Genetics
7.3 Objective questions, answers and explanations
Chapter - 8 Genetics - II : Molecular Genetics
8.1 Genome
8.2 Transposable elements
8.3 Gene
8.4 Organization of chromatin
8.5 Chromosomes
8.6 Molecular Structure of DNA
8.7 Repeated DNA sequence
8.8 DNA replication
8.9 Replication model
8.10 DNA repair
8.11 Ribonucleic acid (RNA)
8.12 Transcription and processing of RNA
8.13 Genetic code
8.14 Protein synthesis
8.15 Post-Translational processing of protein
8.16 Regulation of gene expression
8.17 Gene mutation
8.18 Objective questions, answers and explanations
Chapter - 9 Advanced Biotechnology
9.1 Recombinant DNA technology
9.2 Plant Biotechnology
9.3 Animal Biotechnology
9.4 Objective questions, answers and explanations
Chapter - 10 Enzyme Science And Technology
10.1 Introduction
10.2 Classification of enzymes
10.3 Mechanism of enzyme action
10.4 Enzyme kinetics
10.5 Enzyme inhibition
10.6 Multisubstrate reactions
10.7 Kinetics of Bi-Bi reactions
10.8 Allosteric enzymes, Isoenzymes, Abzymes, Ribozymes, Lysozymes
10.9 Immobilization of enzymes
10.10 Applications of enzymes
10.11 Objective questions, answers and explanations
Chapter - 11 Biochemical Engineering and Bioprocess Technology
11.1 Microbial growth kinetics
11.2 Media formulations
11.3 Sterilizations
11.4 Design of a fermenters
11.5 Mass Transfer
11.6 Aeration and agitation
11.7 Fluid rheology
11.8 Heat Transfer
11.9 Scale-up
11.10 Downstream processing
11.11 Material and energy balance
11.12 Objective questions, answers and explanations
Chapter - 12 Bioinformatics
12.1 Introduction
12.2 Biological database
12.3 Sequence alignments
12.4 Search tools
12.5 Structure alignments
12.6 Phylogenetic analysis
12.7 Building of a tree
12.8 Protein identification
12.9 Gene prediction
12.10 Practical experiments
12.11 Genomics
12.12 Microarrays
12.13 Proteomics
12.14 Protein-Protein & Protein – DNA interaction
12.15 Protein Microarrays
12.16 Objective questions, answers and explanations
SECTION II : GENERAL APTITUDE
PART I. VERBAL ABILITY
1. English Grammar
2. Sentence Completion
3. Synonyms
4. Antonyms
5. Reasoning Ability
PART II. NUMERICAL ABILITY
1. Numbers and Algebra
2. Percentage and Its Applications
3. Time and Work
4. Ratio, Proportion and Mixtures
5. Permutations and Combinations & Probability
6. Miscellaneous
SECTION III : ENGINEERING MATHEMATICS
1. Linear Algebra
2. Calculus
3. Probability and Statistics
4. Numerical Methods
5. Differential Equations
